Generation and characterisation of the CRISPR/Cas9-mediated Clk null Bombyx mori.

(A) Schematic representation of the B. mori Clk genomic region spanning ~39 kb. The 5’ and 3’ UTRs map in exons 1, 2 and 14, respectively. (B) Clk CDS spanning 1941 bp from exons 2 to 14; bHLH and PAS functional domains are shown in o...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Daniel J. Brady (20622465) (author)
مؤلفون آخرون:	Alessio Saviane (18196120) (author), Matteo Battistolli (20623724) (author), Irene Varponi (20623727) (author), Federica Barca (20623730) (author), Kunihiro Shiomi (120424) (author), Silvia Cappellozza (6437528) (author), Federica Sandrelli (464731) (author)
منشور في:	2025
الموضوعات:	Biochemistry Genetics Physiology Ecology Developmental Biology Biological Sciences not elsewhere classified silk production increasing physiological processes regulating null allele ), molecular mechanisms driving key economic traits global silk production enhanced silk production egg hatching rhythms div >< p animal feed underscores advancing sustainable sericulture late instar larvae including adult eclosion >< sup >< pupal weight increasing bombyx mori </ circadian clock functions circadian clock gene mori clk </ pupal weight mori </ circadian clock clock </ clk </ insect larvae gene disruption adult heads ></ sup mediated circadian disrupted circadian clk contributes b </ 29 </ 1922 </ type controls study investigates study highlights pleiotropic effects mutant strain mediated mutagenesis livelihoods worldwide independently generated growing demand future research findings provide determining whether controlled behaviors constant darkness cocoon components biomedical products >&# 916 7 %,
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Generation and characterisation of the CRISPR/Cas9-mediated <i>Clk</i> null <i>Bombyx mori</i>.

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