Results based on the subsampling procedure to simulate single cell data.

<p><b>(a)</b> Data matrices (column one) and detected domain boundaries (columns 2-4 for CaTCH, HiCseg, and TopDom, respectively); row 1 shows the original bulk count matrix, while rows 2-4 provide, respectively, the KR-normalized, SWS3s, RWR0.1, results from one subsample. Note th...

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Päätekijä:	Yongqi Liu (5464067) (author)
Muut tekijät:	Shili Lin (25251) (author)
Julkaistu:	2025
Aiheet:	Medicine Genetics Biotechnology Developmental Biology Cancer Plant Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified topologically associated domains taking correct identification optimal parameter values dimensional hierarchical structure extensive analytical analyses downstream tad analyses current study provides achieve good performance xlink "> hi single cell hi real data applications assessment </ p answer biological questions based approaches prior data quality improvement performing random walks including random walk performing analyses biological questions data quality random walks simulation study performance success little improvement based approaches random walking random walk unrealistic scenario routinely generated range interactions practical guidelines necessary step little justification limited number end point empirical investigation developed accordingly chromosome three cautionary note better understanding &# 8220
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Results based on the subsampling procedure to simulate single cell data.

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