Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf

Introduction<p>Platinum-based chemopotentiation by poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) has been confirmed in some non-small-cell lung carcinoma (NSCLC) models, but the molecular mechanisms of PARPi synergy with chemotherapeutics remain poorly clarified. This study aimed to e...

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Main Author: Nevena Grdović (394542) (author)
Other Authors: Anja Tolić (12356555) (author), Mirna Jovanović (6324551) (author), Jovana Rajić (12356561) (author), Marija Đorđević (12356564) (author), Marijana Stojanović (22489306) (author), Stefan Marković Hadžić (22489309) (author), Tijana Marković (22489312) (author), Ana Sarić (21368240) (author), Svetlana Dinić (394543) (author), Jelena Arambašić Jovanović (12356570) (author), Mirjana Mihailović (394547) (author), Ana Podolski-Renić (289289) (author), Milica Pešić (289295) (author), Melita Vidaković (309714) (author), Aleksandra Uskoković (394545) (author)
Published: 2025
Subjects:
Cell Biology
non-small-cell lung carcinoma cells
chemosensitivity
PARP inhibitor
niraparib
5hmC
ten–eleven translocations enzymes
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