Primary, secondary, and genomic structure of the viral interleukin-4 homolog.

<p>(A) Amino acid alignment of vIL-4 with homologs from selected species. (B) Secondary structure probability of the vIL-4 amino acid sequence as predicted by JPRED2. (C) Signal peptide domain probability as predicted by SignalP 6.0; indicated are the N-terminal domain [‘N’], hydrophobic domai...

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מחבר ראשי:	Jeremy D. Volkening (13030758) (author)
מחברים אחרים:	Stephen J. Spatz (4341484) (author), Maricarmen Garcia (21772671) (author), Teresa A. Ross (2066359) (author), Daniel A. Maekawa (21772674) (author), Kenneth S. Rosenthal (21772677) (author), Ana C. Zamora (21772680) (author), April Skipper (21772683) (author), Julia R. Blakey (21772686) (author), Rashan Paudel (21772689) (author)
יצא לאור:	2025
נושאים:	Medicine Microbiology Genetics Evolutionary Biology Immunology Infectious Diseases Virology Biological Sciences not elsewhere classified suggested direct capture stimulation assay showed natural cytokine signaling macrophage cell line length cdna sequencing confirmed using lc cell culture compared intron gene structure tertiary levels based sequenced iltv genomes infectious laryngotracheitis virus enhance virus replication conserved gene structure div >< p 4 knockout compared viral genome predicted 8 ), il iltv genome expressing recombinant chicken il expressed viral il viral il 4 gene viral mimics precisely conserved highly expressed comparable levels 5 ), vertebrate il functional il vivo </ vivo ,</ vitro </ vertebrate interleukin vertebrate homologs subsequently identified results represent protein expression phylogenetic analyses persisting within perpetuating strategies parental strain mature transcript infected cells immune response galliformes </ functional interleukin first report computational modeling cellular receptors 4 homologs
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Primary, secondary, and genomic structure of the viral interleukin-4 homolog.

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