Base-Promoted One-Pot Four-Component Domino Strategy Involving Aldehydes and Ketones to Access Multifunctionalized Dihydropyridinones

Base-Promoted One-Pot Four-Component Domino Strategy Involving Aldehydes and Ketones to Access Multifunctionalized Dihydropyridinones

The synthesis of multifunctionalized dihydropyridinones from aldehydes and ketones involves at least a three-step process, making route shortening a challenging task, especially in achieving a one-pot four-component synthesis via aldehydes and ketones precondensation. Herein, we discovered a [1 + 2...

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Bibliographic Details
Main Author: Hao Lu (354247) (author)
Other Authors: Xinyu Li (568185) (author), Zhiqing Wang (830081) (author), Peng Du (193248) (author), Shuang-Feng Yin (1478986) (author), Nobuaki Kambe (1621282) (author), Renhua Qiu (1478992) (author)
Published: 2024
Subjects:
Biochemistry
Genetics
Physiology
Pharmacology
Biotechnology
Ecology
Immunology
Infectious Diseases
Space Science
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Information Systems not elsewhere classified
oac ), respectively
making route shortening
initially combining aldehydes
commercially available ketones
4 </ sub
access multifunctionalized dihydropyridinones
multifunctionalized dihydropyridinones
rapid access
tetrasubstituted pyridines
step process
novel concept
meldrum ’
ketones precondensation
ketones involves
derived heterocycles
conveniently converted
challenging task
ammonium acetate
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