Membrane Binding and Cholesterol Sensing Motif in Mycoplasma genitalium FtsZ: A Novel Mode of Membrane Recruitment for Bacterial FtsZ

Cell division in bacteria is initiated by constriction of the Z-ring comprising two essential proteins, FtsZ and FtsA. Though the essential function of the Z-ring in bacterial division has been established, the precise roles of FtsZ and FtsA in the constriction process remain elusive. Due to the min...

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Bibliographic Details
Main Author:	Soumyajit Dutta (21001694) (author)
Other Authors:	Sakshi Poddar (21001697) (author), Joyeeta Chakraborty (3717592) (author), Ramanujam Srinivasan (5665996) (author), Pananghat Gayathri (4608130) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Microbiology Cell Biology Genetics Molecular Biology Evolutionary Biology Immunology Infectious Diseases phylogenetically distinct group obtaining mechanistic insights ftszs lack conservation cholesterol sensing motif terminal peptide sequence terminal amphipathic helix ideal model system globular ftsz domain 113 mycoplasma species ftsa protein sequences mycoplasma genitalium ftsz terminal extensions mycoplasma genitalium ftsa system corresponding sequences 12 species genitalium ftsz precise roles novel mode new perspective minimal number membrane recruitment membrane binding membrane attachment less mycoplasmas functional variations experimentally prove essential function comparative analysis bacterial division
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Membrane Binding and Cholesterol Sensing Motif in Mycoplasma genitalium FtsZ: A Novel Mode of Membrane Recruitment for Bacterial FtsZ

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