Knockdown of CYP1B1 inhibited monocytes activation and tryptophan metabolism.

<p>(A-C) RT-qPCR for the expressions of proinflammatory cytokines. (D-E) Transwell assay of monocytes. (F-G) Western blot for the expression of TDO2. *, P < 0.05, compared with Control group; &, P < 0.05, compared with LPS group.</p>

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Príomhchruthaitheoir:	Li-Hong Chen (610826) (author)
Rannpháirtithe:	Wei-Ru Lin (414546) (author), Hui-Rong Hu (20836649) (author), Zhi-Yuan Chen (3329769) (author), Yan-Hui Wang (5407355) (author)
Foilsithe / Cruthaithe:	2025
Ábhair:	Biochemistry Medicine Cell Biology Genetics Molecular Biology Physiology Immunology Developmental Biology Marine Biology Cancer Hematology Infectious Diseases Virology Computational Biology Chemical Sciences not elsewhere classified including batch normalization evaluated using transcription candidate differential gene blood samples rna cyp1b1 dramatically decreased cell sequencing analysis sepsis still needs proinflammatory cytokines expression related gene cyp1b1 xlink "> cyp1b1 sepsis </ p xlink "> differential analysis related deg blood tissues namely cyp1b1 bioinformatics analysis without sepsis western blot translational level significantly upregulated r software primarily expressed obviously increased multiple diseases important role immune response immune characteristics geo database extract data expression level &# 8217
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Knockdown of CYP1B1 inhibited monocytes activation and tryptophan metabolism.

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