Signal ratio <i>R</i>/2 = (<i>S</i>2/2<i>S</i>1) computed using Equation S3 in S1 File for successive application of a gradient echo pulse sequence with flip angles <i>θ</i>₁ and <i>θ</i>₂, where <i>θ</i>₂ = 2<i>θ</i>₁ (red) and <i>θ</i>₂ = 3<i>θ</i>₁ (blue).

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