Supplementary Figure S3 from Biomarker Analysis and Treatment Dynamics Following Preoperative Ipilimumab plus Nivolumab in Locally Advanced Urothelial Cancer from the Phase IB NABUCCO Study

Supplementary Figure S3 from Biomarker Analysis and Treatment Dynamics Following Preoperative Ipilimumab plus Nivolumab in Locally Advanced Urothelial Cancer from the Phase IB NABUCCO Study

<p>Mutational analysis DDR genes. Fraction and type of alterations for various DNA damage response genes in responders (blue) and non-responders (orange). The different treatment arms are depicted in light green (arm 1), dark green (arm 2A) and lilac (arm 2B).</p>

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Dettagli Bibliografici
Autore principale: Chantal F. Stockem (19663331) (author)
Altri autori: Alberto Gil-Jimenez (19663325) (author), Hamza Ali (22247032) (author), Jeroen van Dorp (19663316) (author), Nick van Dijk (22247035) (author), Maurits L. van Montfoort (19663343) (author), Maartje Alkemade (15120047) (author), Annegien Broeks (15049023) (author), Iris M. Seignette (16797655) (author), Erik Hooijberg (16797661) (author), Wim Brugman (19663328) (author), Rhianne Voogd (22247038) (author), Bas W.G. van Rhijn (19663334) (author), Laura S. Mertens (19663337) (author), Jeantine M. de Feijter (22247041) (author), Niven Mehra (15011036) (author), Antoine G. van der Heijden (19663340) (author), Richard P. Meijer (22247044) (author), Britt B.M. Suelmann (22247047) (author), Wouter Scheper (22247050) (author), Lodewyk F.A. Wessels (15037422) (author), Daniel J. Vis (19663346) (author), Michiel S. van der Heijden (19663349) (author)
Pubblicazione: 2025
Soggetti:
Cancer
Tumor Biology
Cancer Detection and Diagnosis
Immuno-oncology
Biomarkers
Genitourinary Cancers
Bladder cancer
Immunotherapy
Checkpoint blockade
Tumor Microenvironment
Immune cells and the microenvironment
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