Graphene-MoS<sub>2</sub> Heterojunction Nanopores: Enhanced ssDNA Capture via Asymmetric Charge Control

DNA sequencing through nanopores requires both high-throughput detection and precise timing control. However, single-material nanopores face conflicting demands regarding capture efficiency and translocation control. To tackle these challenges, all-atom molecular dynamics (MD) simulations were perfo...

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Main Author:	Yuanshuo Zhang (16529409) (author)
Other Authors:	Mingming Ding (1674565) (author)
Published:	2025
Subjects:	Biophysics Medicine Molecular Biology Biotechnology Developmental Biology Space Science Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Physical Sciences not elsewhere classified sup >+</ sup prolonged residence time negative surface charging negative charging generates negative charging enhances negative charging creates atom molecular dynamics stronger electroosmotic force reduced force fluctuations precise timing control asymmetric charge control 2 </ sub electrophoretic force translocation control throughput detection terminal nucleotides stranded dna nanopores requires molecule sequencing interaction leads heterojunction nanopores findings suggest favorable orientations bulk value 45 times 17 times
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Graphene-MoS<sub>2</sub> Heterojunction Nanopores: Enhanced ssDNA Capture via Asymmetric Charge Control

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