Anti-<i>Streptococcus suis</i> IgG titers, but not their avidity, increase with repeated infections.

Anti-<i>Streptococcus suis</i> IgG titers, but not their avidity, increase with repeated infections.

<p>Groups of C57BL/6 mice were infected with 1 x 10<sup>6</sup> CFU doses of live <i>S</i>. <i>suis</i> serotype 2 strain P1/7. (A) Timeline of the infections performed in the different groups of mice with serum collection on day 35 for all groups. (B) Anti-...

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Bibliographic Details
Main Author:	Dominic Dolbec (5509040) (author)
Other Authors:	Mélanie Lehoux (5665552) (author), Alexis Asselin de Beauville (17817500) (author), Astrid Zahn (17817503) (author), Javier Marcelo Di Noia (17817506) (author), Mariela Segura (135590) (author)
Published:	2024
Subjects:	Microbiology Neuroscience Ecology Immunology Infectious Diseases Virology poorly understood despite evaluated germinal center several igg subclasses effective vaccine exists antibody response plays dependent germline igm type mice sera >- igg production produce optimal anti prevents gc formation maintained igm production cps igm titers streptococcus suis </ b cell kinetics cps igm production total igg suis </ potential vaccine humoral response b cells largely igm importance igm mice infected >) mice zoonotic agent vitro </ tcrb -/-</ swine farms somatic hypermutation serotype 2 sap deficiency provide insight potentially anti opsonophagocytic activity mouse model likely relevance isotype switching future development developed gc deficient (< control bacteremia capsular polysaccharide bacterial killing bacterial clearance anti -< ablated anti
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