Supplementary Figure 5 from <i>ALK</i> Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma

Supplementary Figure 5 from <i>ALK</i> Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma

<p>Supplementary Figure 5: Single-cell RNA Sequencing and IHC examination of ALK in human neural development and immature neural cells. A. 2D representation of human brain cell subtypes (48 samples) during cortex development using a single cell RNA-seq atlas (cortex-dev.cells.ucsc.edu) shows t...

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Hlavní autor: Anne-Florence Blandin (15056366) (author)
Další autoři: Ross Giglio (15056369) (author), Maya Srikanth Graham (15056372) (author), Guadalupe Garcia (15056375) (author), Seth Malinowski (15056378) (author), Jared K. Woods (15056381) (author), Shakti Ramkissoon (15056384) (author), Lori Ramkissoon (15056387) (author), Frank Dubois (15056390) (author), Kathleen Schoolcraft (15056393) (author), Jessica Tsai (15056396) (author), Dayle Wang (15056399) (author), Robert Jones (15056402) (author), Jayne Vogelzang (15056405) (author), Kristine Pelton (15056408) (author), Sarah Becker (15056411) (author), Fiona Watkinson (15056414) (author), Claire Sinai (15056417) (author), Elizabeth F. Cohen (15056420) (author), Matthew A. Booker (15056423) (author), Michael Y. Tolstorukov (15056426) (author), Veerle Haemels (15056429) (author), Liliana Goumnerova (15056432) (author), Karen Wright (15056435) (author), Mark Kieran (15056438) (author), Katie Fehnel (15056441) (author), David Reardon (15056444) (author), Arnault Tauziede-Espariat (15056447) (author), Rishi Lulla (15056450) (author), Benjamin Carcamo (15056453) (author), Stanley Chaleff (15056456) (author), Alain Charest (15056459) (author), Frederik De Smet (14957559) (author), Azra H. Ligon (15056462) (author), Adrian Dubuc (15056465) (author), Melanie Pages (15056468) (author), Pascale Varlet (15056471) (author), Patrick Y. Wen (15056474) (author), Brian M. Alexander (15019467) (author), Susan Chi (15056477) (author), Sanda Alexandrescu (9122099) (author), Ralf Kittler (14864988) (author), Robert Bachoo (15056480) (author), Pratiti Bandopadhayay (15056483) (author), Rameen Beroukhim (15056486) (author), Keith L. Ligon (14958845) (author)
Vydáno: 2025
Témata:
Cancer
Cancer Biology
Molecular and Cellular Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Methods and Technology
Biomarkers
Cell Signaling
Receptors
CNS Cancers
Gliomas, Glioblastomas
Drug Targets
Protein kinase & phosphatase drug targets
Oncogenes & Tumor Suppressors
Oncogenes
Pediatric Cancers
Preclinical Models
Xenograft models
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