Table 3_TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease.xlsx

Table 3_TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease.xlsx

Introduction<p>Triggering receptor expressed on myeloid cells-2 (TREM2) variants have been identified as risk factors for neurodegenerative disease, including Alzheimer’s disease. TREM2 is a cell surface receptor on microglia that regulates homeostatic and immunomodulatory functions, including...

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Bibliographic Details
Main Author: Sarah M. Carpanini (13009171) (author)
Other Authors: Barry M. Bradford (7361267) (author), Alessio Alfieri (5246843) (author), Pedro Piccardo (331519) (author), Jimena Monzón-Sandoval (3182745) (author), Deborah Brown (2889458) (author), Aileen Boyle (274952) (author), Aleksandra Pokrovskaya (17149684) (author), Neil A. Mabbott (7361273) (author), Jean Manson (17218057) (author), Barry W. McColl (6709970) (author)
Published: 2025
Subjects:
Neuroscience
TREM2
neurodegenerative disease
microglial reactivity
pathology
prion disease
neuroinflammation
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