Image_2_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.tif

Image_2_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.tif

<p>DNMT3A mutations play a prominent role in clonal hematopoiesis and myeloid neoplasms with arginine (R)882 as a hotspot, however the clinical implications of R882 vs. non-R882 mutations in myeloid neoplasms like myelodysplastic syndrome (MDS) is unclear. By data mining with publicly accessib...

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Bibliographic Details
Main Author: Majd Jawad (12157533) (author)
Other Authors: Michelle Afkhami (5012111) (author), Yi Ding (172783) (author), Xiaohui Zhang (81778) (author), Peng Li (69518) (author), Kim Young (56698) (author), Mina Luqing Xu (12157536) (author), Wei Cui (92129) (author), Yiqing Zhao (581205) (author), Stephanie Halene (8807855) (author), Aref Al-Kali (3466037) (author), David Viswanatha (12157539) (author), Dong Chen (448284) (author), Rong He (25641) (author), Gang Zheng (29050) (author)
Published: 2022
Subjects:
Cancer
Cancer Cell Biology
Cancer Diagnosis
Cancer Genetics
Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
Chemotherapy
Haematological Tumours
Molecular Targets
Radiation Therapy
Solid Tumours
Oncology and Carcinogenesis not elsewhere classified
DNMT3A
genetics
R882 mutations
myelodysplastic syndromes
acute myeloid leukemia
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