Confirm the outcome of the hits from 5JI4 libraries.

A. An example of peptide 5ji4-RSP-1 in vitro re-folding. TIC from LC/MS runs before and after re-folding are shown on the left with peaks’ m/z on the right. After two days of re-folding, both peaks 2 and 3 contain expected m/z (indicated by green triang...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Fei Cai (43088) (author)
مؤلفون آخرون:	Yuehua Wei (1515808) (author), Daniel Kirchhofer (769756) (author), Andrew Chang (578485) (author), Yingnan Zhang (270437) (author)
منشور في:	2024
الموضوعات:	Biophysics Biochemistry Biotechnology Biological Sciences not elsewhere classified Information Systems not elsewhere classified yeast surface display naturally occurring disulfide natural language understanding high accuracy across de novo </ attractive therapeutic modalities alanine scanning experiment good folding properties enhanced folding efficiency highly functional libraries findings could pave exhibiting highly stable work advances peptide utilizing multiple dcps div >< p >- designed hcp discovering peptide therapeutics original library design peptide scaffolds played libraries could spontaneous folding stable topology library design peptide scaffolds developing therapeutics based therapeutics techniques used scale dataset robust platform rapid prediction prediction model poor chemical physical stability model based like scaffolds key residues insights gained first generated emerging modality either agonize efficient development crucial role broad range
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Confirm the outcome of the hits from 5JI4 libraries.

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