Supplementary Figure S2 from Repurposing the DNA Labeling Agent EdU for Therapy against Heterogeneous Patient Glioblastoma

Supplementary Figure S2 from Repurposing the DNA Labeling Agent EdU for Therapy against Heterogeneous Patient Glioblastoma

<p>Figure S2: Features of glioblastoma models used to assess therapeutic potential of EdU. The features in red are less than desirable, blue are moderately desirable, and green are ideal. As such, the compounds were tested on multiple cell culture platforms to supplement the weaknesses of indi...

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Autore principale: Humeyra Kaanoglu (21903844) (author)
Altri autori: Adebimpe Adefolaju (21903847) (author), Casey Fraley (21903850) (author), Mariah Shobande (21903853) (author), Rajaneekar Dasari (21903856) (author), Breanna Mann (21903859) (author), Noah Bell (21903862) (author), Stephen T. Keir (18724623) (author), Dominique Higgins (21903865) (author), David E. Kram (15110825) (author), Shawn D. Hingtgen (21903868) (author), Aziz Sancar (21903871) (author), Andrew B. Satterlee (21903874) (author)
Pubblicazione: 2025
Soggetti:
Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
Clinical Research and Trials
Methods and Technology
CNS Cancers
Gliomas, Glioblastomas
Dna Damage And Repair
DNA damage
Precision Medicine
Preclinical Models
Small Molecule Agents
Translational Research
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