Figure 6 from Extracellular Vesicle Secretion by Leukemia Cells <i>In Vivo</i> Promotes CLL Progression by Hampering Antitumor T-cell Responses

Figure 6 from Extracellular Vesicle Secretion by Leukemia Cells <i>In Vivo</i> Promotes CLL Progression by Hampering Antitumor T-cell Responses

<p>sEVs are crucial for CLL development by impairing the antitumor immune response <i>in vivo.</i><b>A,</b> Generation of a new TCL1-RAB27DKO mouse model. <b>B,</b> Detection of the human <i>TCL1</i> transgene and Rab27b excision in gDNA of C57BL...

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Auteur principal: Ernesto Gargiulo (15134961) (author)
Autres auteurs: Elodie Viry (15134964) (author), Pablo Elías Morande (15134967) (author), Anne Largeot (15134970) (author), Susanne Gonder (15134973) (author), Feng Xian (15134976) (author), Nikolaos Ioannou (15134979) (author), Mohaned Benzarti (15134982) (author), Felix Bruno Kleine Borgmann (15134985) (author), Michel Mittelbronn (15134988) (author), Gunnar Dittmar (15134991) (author), Petr V. Nazarov (15134994) (author), Johannes Meiser (15134997) (author), Basile Stamatopoulos (15135000) (author), Alan G. Ramsay (15021857) (author), Etienne Moussay (15135003) (author), Jérôme Paggetti (15135006) (author)
Publié: 2025
Sujets:
Cancer
Tumor Biology
Immuno-oncology
Methods and Technology
Hematological Cancers
Leukemias
Lymphomas
Immunology
T cell exhaustion
Tumor resistance to immune response
Preclinical Models
Animal models of cancer
Tumor Microenvironment
Immune cells and the microenvironment
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