Nonsense allele results in mislocalization of Ksr1p.

Nonsense allele results in mislocalization of Ksr1p.

<p>(A) Ribbon models produced by Alphafold [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012497#ppat.1012497.ref062" target="_blank">62</a>] predictions are shown for <i>C</i>. <i>albicans</i> Ksr1pA and Ks...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Pétra Vande Zande (17628246) (author)
مؤلفون آخرون:	Cécile Gautier (19513899) (author), Nora Kawar (19513902) (author), Corinne Maufrais (516662) (author), Katura Metzner (15324829) (author), Elizabeth Wash (19513905) (author), Annette K. Beach (18083374) (author), Ryan Bracken (19513908) (author), Eli Isael Maciel (9984317) (author), Nívea Pereira de Sá (19513911) (author), Caroline Mota Fernandes (10575782) (author), Norma V. Solis (8339217) (author), Maurizio Del Poeta (7254743) (author), Scott G. Filler (202661) (author), Judith Berman (38077) (author), Iuliana V. Ene (8842898) (author), Anna Selmecki (38074) (author)
منشور في:	2024
الموضوعات:	Genetics Evolutionary Biology Ecology Infectious Diseases Computational Biology sphingolipid biosynthesis pathway population genome sequencing major fungal pathogen global health threat div >< p displays high rates copy number variation azole susceptibility relative antifungal drug adaptation candida albicans </ affect fluconazole resistance chromosome 4 cnv chromosome 4 albicans </ evolutionary adaptation azole resistance chromosome r ksr1 </ c </ sequential evolution isolate involving initial cnv fold decrease fluconazole tolerance evolutionary processes could synergize compelling example clonal interference also detected
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