Data Sheet 5_Phosphodiesterase 7: a potential novel therapeutic target in ovarian cancer.pdf

Data Sheet 5_Phosphodiesterase 7: a potential novel therapeutic target in ovarian cancer.pdf

Introduction<p>Chemoresistance and disease relapses in epithelial ovarian cancer (EOC) highlight the need for novel therapeutic strategies. Here, we investigated phosphodiesterase 7A (PDE7A) as a potential target in ovarian cancer treatment.</p>Methods<p>Gene expression was perform...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Nayara Gusmão Tessarollo (18228556) (author)
مؤلفون آخرون: Isabella dos Santos Guimarães (18228559) (author), Diandra Zipinotti dos Santos (21477563) (author), Taciane Barbosa Henriques (18228565) (author), Paulo Cilas Morais Lyra-Junior (21477566) (author), Josiany Carlos de Souza (18228580) (author), Tatiana Massariol Pimenta (18228577) (author), Bárbara da Silva Martins (21477569) (author), Solenny Maria Silva Butzene (18228589) (author), José Matheus Simões Padilha (21477572) (author), Leide Laura Figueiredo Maciel (18228571) (author), João Carlos de Aquino Almeida (21477584) (author), Ian Victor Silva (3750022) (author), Leticia Batista Azevedo Rangel (21477587) (author)
منشور في: 2025
الموضوعات:
Pharmacology
ovarian cancer
phosphodiesterase 7-A
PI3K/AKT/mTOR signaling pathway modulation
paclitaxel
mitochondrial cristae morphology alteration
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