Cholesterol biosynthetic process CKO vs K5Cre GO: Biological Processes.

Cholesterol biosynthetic process CKO vs K5Cre GO: Biological Processes.

<p>Cholesterol biosynthetic process CKO vs K5Cre GO: Biological Processes.</p>

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Kevin J. Mills (9270966) (author)
مؤلفون آخرون:	Michael Doyle (3013599) (author), John S. House (7485818) (author), John G. Witherspoon (21601668) (author), Daniel Krakko (21601671) (author), Whitney L. Stutts (1466218) (author), Jessie R. Chappel (19235764) (author), Jonathan R. Hall (6371993) (author), Erin S. Baker (1320990) (author), Robert C. Smart (14904738) (author)
منشور في:	2025
الموضوعات:	Biophysics Biochemistry Medicine Cell Biology Genetics Molecular Biology Physiology Developmental Biology Hematology Virology Computational Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified gene sets related gene sets associated enhancer binding protein div >< p transepidermal water loss differentially regulated genes rnaseq data analysis 165 significantly decreased skin barrier integrity skin barrier function epidermal barrier function free fatty acids 82 significantly increased dysregulated lipid biosynthesis fatty acids barrier formation also dysregulated lipidomic analysis lipid biosynthesis epidermal lipidome epidermal keratinocytes decreased class analysis showed also decreased loss c sphingomyelin class skh1 mice rna isolated results indicate present study major regulator functional consequences downregulated genes conditional knockout cholesterol species approximate doubling abundantly expressed
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