Compartmental diagram of the selection process over multiple gonotrophic cycles for IRM strategies.

<p>The framework of the multiple cycle model allows for multiple different strategies to be evaluated: Red indicates only a single insecticide is deployed, orange is a mixture, blue is a micro-mosaic, and green is a combination of ITN and IRS. These different strategies apply differing levels...

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Bibliographic Details
Main Author:	Neil Philip Hobbs (20748043) (author)
Other Authors:	Ian Hastings (340524) (author)
Published:	2025
Subjects:	Medicine Biotechnology Evolutionary Biology Cancer Statistics Science Policy Infectious Diseases Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified selection differentials accounting reduced dose mixtures often little difference model simulations indicates individual survival depends gonotrophic cycle model dose mixtures remain direct policy relevance demonstrating model assumptions insecticide selection differential multiple gonotrophic cycles models increases confidence polygenic resistance may link resistance management resistance management published polygenic insecticide efficacy insecticide decay resistance ). cross resistance two methods successive generations specific evaluations resistant individuals predictions especially population survive operational realism operational effectiveness monogenic models life span increasing biological future applications dynamic method disease transmission computational models appropriate assumption age distributions
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Compartmental diagram of the selection process over multiple gonotrophic cycles for IRM strategies.

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