A genome-wide association study using HapMap cell lines reveals modulators of cellular response to cyclophosphamide

A genome-wide association study using HapMap cell lines reveals modulators of cellular response to cyclophosphamide

<p>This study identifies single-nucleotide polymorphisms (SNPs) associated with cellular response to cyclophosphamide (CTX) using phosphoramide mustard (PM), its primary cytotoxic metabolite, and explores the downstream consequences for breast cancer (BC) patients.</p> <p>We analyz...

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Bibliographic Details
Main Author: Mohammed O. Gbadamosi (21357009) (author)
Other Authors: Neha Bhise (10951269) (author), Taraswi Mitra Ghosh (11795375) (author), Elizabeth K. Molchan (21357012) (author), Kathleen Streeks (21357015) (author), Jason Puglise (21357018) (author), Alyssa Ohaegbulam (21357021) (author), Mariana Makarem (21357024) (author), Oluwaseyi Olabige (21357027) (author), Changlin Yang (5022152) (author), Luisel Ricks-Santi (15171469) (author), Duane A. Mitchell (8066063) (author), Brooke L. Fridley (9434057) (author), Jatinder K. Lamba (10038865) (author)
Published: 2025
Subjects:
Cell Biology
Genetics
Biotechnology
Cancer
Hematology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
Cyclophosphamide
pharmacogenomics
breast cancer
HapMap
pharmacodynamics
SNPs
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