Transcriptomic studies of specific brain tissues in which a diagnosis of Alzheimer’s disease did not result in a significant change to global expression profile.

<p>Study GSE36980 (a) comprised 15 frontal cortex samples from individuals diagnosed with Alzheimer’s disease (AD FC), 18 frontal cortex samples from healthy controls (HC FC), 10 temporal cortex samples from individuals diagnosed with Alzheimer’s disease (AD TC), 19 temporal cortex samples fro...

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Main Author:	Benjamin S. Pickard (21276556) (author)
Published:	2025
Subjects:	Biochemistry Microbiology Cell Biology Genetics Molecular Biology Immunology Biological Sciences not elsewhere classified shift dynamically across public transcriptomic datasets proton pump inhibitors processes particularly sensitive may permit efficient including alzheimer ’ included known toxins g sequence composition en bloc </ average composition change amino acid availability entirely new perspective distinct baseline profile dependent transcriptional competence autoimmune disorders ), average expression change transcript levels gene multiple disease states mechanism helped mitigate div >< p conventional transcriptomic analysis global expression regulation gene expression offers also significantly distorted nucleobase supply interacts global profile global expression transcriptional reprogramming new mechanism interactions ), also proposed protein expression nucleobase proportion nucleobase analogues global scale gene ontologies viral infection useful distinction type displays thus revealing specific demands simple adjustment separate organ recently showed menstrual cycle measurement allows key roles higher organisms extreme compositions equivalently affected drug action disease susceptibility disease aetiopathology circadian day
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Transcriptomic studies of specific brain tissues in which a diagnosis of Alzheimer’s disease did not result in a significant change to global expression profile.

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