Reducing the Dscam1 level rescues the phenotype defect caused by reducing Dscam1 diversity, Related to Fig 7.

(A) The mean survival rates of adult flies of Dscam1 mutants with one copy or two copies of the mutant allele are shown. Reducing the Dscam1 expression level partially rescued the fly viability in homozygous mutants. (B) The mean lifespan of adult flies...

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Main Author:	Haiyang Dong (4783608) (author)
Other Authors:	Lili Wu (559545) (author), Zhechao Wang (1885963) (author), Huiru Qu (22238445) (author), Jinpeng Xie (22238448) (author), Yaoqi Liu (1489525) (author), Jingsong Lv (22238451) (author), Nengcheng Bao (22238454) (author), Jian Zhang (1682) (author), Pengjuan Guo (4783611) (author), Ru Yan (628199) (author), Jiayan Fu (20761787) (author), Jilong Shi (10495370) (author), Ying Fu (173963) (author), Lei Li (29537) (author), Yiwen Du (14125278) (author), Hongru Ma (3975644) (author), Feng Shi (305643) (author), Jianhua Huang (206865) (author), Yongfeng Jin (32438) (author)
Published:	2025
Subjects:	Biochemistry Cell Biology Molecular Biology Evolutionary Biology Ecology Immunology Developmental Biology Hematology correlation analysis revealed changes varied remarkably assess multiple aspects 10 ), whereas canonical neuronal functions separate role essential canonical neuronal self drosophila melanogaster </ dscam1 diversity compared dscam1 isoform diversity isoforms (< 1 drosophila </ isoform diversity dscam1 diversity dscam1 isoform dscam1 </ immune functions astonishing diversity dscam1 isoforms variable cluster specific manner species diversification small fraction self discrimination remains elusive related traits potential number modern expansion modern evolution modern diversification isoforms increased findings suggest dominant drivers developmental contexts 9 clusters
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Reducing the Dscam1 level rescues the phenotype defect caused by reducing Dscam1 diversity, Related to Fig 7.

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