Multiple sequence alignment of <i>Ov</i>-RAL-2 Glutamine-repeat epitope (GRR) showing identical sequence stretches common to some human proteins.

<p>UniProtKB IDs of top human hits Q92896 and P20265 function as transcription factors that play a key role in neuronal differentiation, while P42858 plays a role in microtubule-mediated transport or vesicle function with its N-terminal fragment involved in the formation of autophagic vesicles...

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Main Author:	Derrick Neba Nebangwa (19923731) (author)
Other Authors:	Robert Adamu Shey (5793530) (author), Daniel Madulu Shadrack (19923734) (author), Cabirou Mounchili Shintouo (11482851) (author), Ntang Emmaculate Yaah (19923737) (author), Bernis Neneyoh Yengo (19923740) (author), Mary Teke Efeti (19923743) (author), Ketura Yaje Gwei (19923746) (author), Darling Bih Aubierge Fomekong (19923749) (author), Gordon Takop Nchanji (6439862) (author), Arnaud Azonpi Lemoge (19923752) (author), Fidele Ntie‑Kang (19923755) (author), Stephen Mbigha Ghogomu (4354198) (author)
Published:	2024
Subjects:	Medicine Genetics Immunology Infectious Diseases Astronomical and Space Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified shown great promise harbour substantial numbers global efforts shift div >< p certain adverse effects causes significant eye analytical immunoinformatics algorithms afflicting millions worldwide debilitating tropical disease lacked epitopes identical overall success rate vaccine candidates (< >- 103 antigens vaccine candidates >- 103 disease management >- ral distinct epitopes cell epitopes allergenic epitopes wide range sustained levels skin damage river blindness protein sequences protective immunity ov </ immunogenic limitations human trials human proteome high affinity findings suggest diverse humoral clinical trials clinical development cellular mechanisms analyses revealed absent within 5 years
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Multiple sequence alignment of <i>Ov</i>-RAL-2 Glutamine-repeat epitope (GRR) showing identical sequence stretches common to some human proteins.

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