Creation of the competitive endogenous RNA (ceRNA) regulatory network.

<p>(A) The ceRNA regulatory network included 18 DEmRNAs, 13 DEmiRNAs, and 29 DElncRNAs in PCOS and control group. DEmRNAs, DEmiRNAs, and DElncRNAs are denoted as green triangles, pink circles, and blue diamonds, respectively. (B) A Sankey diagram of the ceRNA network associated with the immune...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Ningning Xie (12054996) (author)
مؤلفون آخرون:	Fangfang Wang (330843) (author), Danqing Chen (822647) (author), Jue Zhou (11515984) (author), Jian Xu (31545) (author), Fan Qu (4763652) (author)
منشور في:	2024
الموضوعات:	Genetics Immunology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified underlying molecular mechanisms significant changes observed related cerna networks predict potential drugs potential drug candidates polycystic ovary syndrome may impact fetal lncrnas expression levels identified 308 demrnas emerging evidence suggests 57 cerna events placental cerna networks functional enrichment analysis immune dysfunction mediated placental growth factor div >< p fetal immune system identifying hub genes whether immune function protein interaction network pcos group ), placental growth immune system hub genes pcos ), gsea analysis control group eight genes transcriptome sequencing study represents significantly elevated reproductive years reactive protein pcos tissues pcos therapy pcos samples neutrophil count lymphocyte count jun </ indicating alterations inaugural attempt hypersensitive c fos </ finally obtained egr1 </ dramatically decreased cxcr2 </ cxcr1 </ cxcl8 </ cxcl11 </ cxcl10 </ currently unexplored connectivity map conducted utilizing common endocrine chemokine pathway 77 demirnas 332 delncrnas
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Creation of the competitive endogenous RNA (ceRNA) regulatory network.

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