Principle component analysis of the expression of mRNA in U937 cells in the presence / absence of fentanyl.

Principle component analysis of the expression of mRNA in U937 cells in the presence / absence of fentanyl.

<p><b>(A)</b> Antiviral, <b>(B)</b> cell death, <b>(C)</b> chemokine, <b>(D)</b> interferon, and <b>(E)</b> NFκB signaling genes that are significantly differentially expressed (red circle = no fentanyl and cyan circle = fentanyl trea...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Janani Madhuravasal Krishnan (19736002) (author)
مؤلفون آخرون: Ling Kong (419944) (author), Heidi L. Meeds (10097746) (author), Krishna M. Roskin (13023719) (author), Mario Medvedovic (1779) (author), Kenneth E. Sherman (7573052) (author), Jason T. Blackard (7573046) (author)
منشور في: 2025
الموضوعات:
Medicine
Genetics
Molecular Biology
Neuroscience
Immunology
Cancer
Mental Health
Infectious Diseases
Virology
time pcr targeting
suppress immunologic responses
optimized treatment strategies
ccr5 chemokine receptors
better understand opioid
opioid use disorder
accelerated disease progression
hiv p24 antigen
enhance viral replication
ccr5 protein levels
u937 cell line
proviral dna levels
chemokine receptor expression
promote hiv replication
hiv proviral dna
synthetic opioid fentanyl
macrophages </ p
proviral dna
hiv replication
hiv protein
expression levels
viral hepatitis
u937 cells
synthetic opioids
severe disease
pol </
illicit use
cell lysates
hiv pathogenesis
xlink ">
virus interactions
varying concentrations
significant decrease
several micrornas
several drugs
primary mdms
investigated thoroughly
infected cells
higher risk
fentanyl compared
drug exposure
develop new
derived macrophages
data demonstrate
culture supernatants
contract infections
cells infected
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