A Sequential Dual-Reagent Paper-Based Analytical Device with Structural Release Control for Point-of-Care Detection of Urinary N‑Acetyl-β‑d‑Glucosaminidase

N-acetyl-β-d-glucosaminidase (NAG) is an important biomarker that indicates early renal tubular damage. Its activity level in urine has been widely used for early detection and monitoring of chronic kidney disease (CKD), particularly diabetic nephropathy. Howeve...

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Автор:	Jie Cheng (294193) (author)
Інші автори:	Taiqiang Zhao (22677110) (author), Jiasheng Yan (10287043) (author), Zhengkang Chu (22677113) (author), Yongmei Tian (560990) (author), Shi Hua (20154516) (author), Meiling Jin (3975752) (author), Peihong Xiao (1395568) (author), Jinhong Guo (613139) (author), Honghua Hu (1272258) (author)
Опубліковано:	2025
Предмети:	Medicine Cell Biology Genetics Biotechnology Developmental Biology Marine Biology Space Science Biological Sciences not elsewhere classified Information Systems not elsewhere classified utilizes structural partitioning system uses vra optical quantitative analysis initiate color development color development process structural release control based analytical device linear detection range standard clinical method nag enzymatic reaction chronic kidney disease 2 </ sup kidney disease programmed control portable device method provides >< sup early detection detection limit care detection β ‑< β -< widely used trigger mechanism strong potential sequential dual requires portability reagent paper r </ programmed delay n </ important biomarker high risk high reproducibility findings highlight correlation coefficient complex instrumentation clinical poct care testing alkaline catalyst activity level achieve time >‑ glucosaminidase >‑ acetyl >- glucosaminidase >- acetyl 6 %, 524 u 5 ).
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A Sequential Dual-Reagent Paper-Based Analytical Device with Structural Release Control for Point-of-Care Detection of Urinary <i>N</i>‑Acetyl-β‑<i>d</i>‑Glucosaminidase

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