Figure 1 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

Figure 1 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

<p>Knocking down SIRT3 caused ATF4 signaling inhibition but not HIF1a. <b>A,</b> Dendrograms from hierarchical clustering of RNA-seq data from three DLBCL cells lines transduced with lentiviruses containing control (scramble) or two SIRT3 shRNAs. <b>B,</b> Heatmap showi...

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Detalhes bibliográficos
Autor principal: Meng Li (79487) (author)
Outros Autores: Matthew R. Teater (15129060) (author), Jun Young Hong (6588914) (author), Noel R. Park (15129063) (author), Cihangir Duy (15112006) (author), Hao Shen (195461) (author), Ling Wang (56577) (author), Zhengming Chen (385056) (author), Leandro Cerchietti (15091552) (author), Shawn M. Davidson (14911596) (author), Hening Lin (1306563) (author), Ari M. Melnick (15110132) (author)
Publicado em: 2025
Assuntos:
Cancer
Molecular and Cellular Biology
Cellular Stress Responses
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Lymphomas
Metabolism
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