Sensitivity of serological detection heuristics in identifying infection status for 99 PCR-positive individuals using serological data only.

Posterior probabilities of recovery for individuals using five detection methods: (A) Four-fold spike rise, (B) Four-fold NCP rise, (C) Seropositive threshold spike, (D) Seropositive threshold NCP, and (E) serojump. Green bars represent individuals infe...

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מידע ביבליוגרפי
מחבר ראשי:	David Hodgson (40958) (author)
מחברים אחרים:	James Hay (13623790) (author), Sheikh Jarju (22209121) (author), Dawda Jobe (9014387) (author), Rhys Wenlock (12901953) (author), Thushan I. de Silva (5648554) (author), Adam J. Kucharski (8190894) (author)
יצא לאור:	2025
נושאים:	Medicine Microbiology Biotechnology Ecology Immunology Science Policy Infectious Diseases Virology Computational Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified novel probabilistic framework enabling deeper insights achieves higher sensitivity interpreting serological data world data revealed outperforming static threshold infer infection status level serological data immune responses generated exposure immune responses longitudinal serological data subsequent antibody kinetics div >< p missed infections based level antibody kinetics inferring infection timing inferred infection timing standard serological heuristics multiple biomarkers post immune responses antibody level antibody kinetics antibody responses serological inference serological datasets serological assays world sars threshold rises longitudinal sars based methods past infections infection rates infection dynamics identifying infections valuable window traditional methods software package simulation studies serojump </ seroconversion thresholds potentially leading often rely observational noise flexible tool findings highlight extracting information demonstrating robustness biomarkers relating binary seropositivity biased estimates
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

Sensitivity of serological detection heuristics in identifying infection status for 99 PCR-positive individuals using serological data only.

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