Program replication depends on the number of cells.

Program replication depends on the number of cells.

<p>Same as <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013387#pcbi.1013387.g007" target="_blank">Fig 7C</a> and D—instead of taking downsamples of unperturbed cells from Replogle et al., 2022, we downsample the entire experiment t...

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Bibliographic Details
Main Author: Matthew Aguirre (9558032) (author)
Other Authors: Jeffrey P. Spence (15317543) (author), Guy Sella (230321) (author), Jonathan K. Pritchard (8027465) (author)
Published: 2025
Subjects:
Genetics
Molecular Biology
Developmental Biology
Infectious Diseases
Computational Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
world network theory
consider future avenues
interpret gene coexpression
gene knockouts within
better understand properties
scale perturbation study
like hierarchical structure
unperturbed cells may
gene regulation
unperturbed states
scale efforts
key properties
systematically describe
remains challenging
recent genome
recapitulate features
perturbation data
new approach
molecular perturbations
modular organization
efficient manner
deeper analysis
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