Figure 4 from Phase II Clinical Trial and Preclinical Evaluation of a Novel CD47 Blockade Combination in Refractory Microsatellite-Stable Metastatic Colorectal Cancer

Figure 4 from Phase II Clinical Trial and Preclinical Evaluation of a Novel CD47 Blockade Combination in Refractory Microsatellite-Stable Metastatic Colorectal Cancer

<p>Pharmacodynamic analyses. <b>A,</b> Multiplex IHC of archival tumor tissue from one patient with disease progression and one patient with PR; <b>B,</b> Percent change (cycle 3 day 1 compared with baseline) in peripheral blood effector CD4<sup>+</sup> (CD4...

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Main Author: Robert W. Lentz (17013559) (author)
Other Authors: Julie Lang (20519739) (author), Todd M. Pitts (17013577) (author), Patrick Blatchford (22652193) (author), Junxiao Hu (16157686) (author), Kimberly R. Jordan (15049505) (author), Adrie Van Bokhoven (22652196) (author), Stacey M. Bagby (17013565) (author), Adrian T.A. Dominguez (19529151) (author), Cameron A. Binns (22652199) (author), Hannah R. Robinson (19529136) (author), Nicole Balmaceda (22652202) (author), Emily Baiyee (22652205) (author), Alexis D. Leal (17013562) (author), Sunnie S. Kim (19529139) (author), S. Lindsey Davis (14032353) (author), Christopher H. Lieu (15018279) (author), Raymond C. Wadlow (22652208) (author), Kristen Spencer (22652211) (author), Aaron J. Scott (15133937) (author), Patrick M. Boland (15037142) (author), Howard S. Hochster (15022088) (author), Wells A. Messersmith (17013568) (author)
Published: 2025
Subjects:
Cancer
Immuno-oncology
Clinical Research and Trials
Clinical Trial Results
Phase II clinical trials
Checkpoint Blockade
Colorectal Cancer
Combination Immunotherapy
Gastrointestinal Cancers
Immunotherapy
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