RECONCILE study inclusion and exclusion criteria.

RECONCILE study inclusion and exclusion criteria.

<div><p>Introduction</p><p>RECONCILE (ClinicalTrials.gov:NCT04340245) will identify molecular and radiomic markers associated with clinical progression and radiological progression events in a cohort of localised, newly diagnosed Gleason 3 + 4 tumours. Molecular markers will...

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Bibliographic Details
Main Author: Teresa Marsden (12133267) (author)
Other Authors: Gerhardt Attard (120990) (author), Shonit Punwani (3547364) (author), Francesco Giganti (727736) (author), Alex Freeman (127608) (author), Aiman Haider (12114733) (author), Anna Wingate (12906113) (author), Norman Williams (5101406) (author), Tom Syer (12133273) (author), Nora Pashayan (64158) (author), Caroline M. Moore (7169102) (author), Mark Emberton (3547379) (author), Clement Orczyk (7311095) (author)
Published: 2024
Subjects:
Medicine
Cell Biology
Genetics
Biotechnology
Cancer
Infectious Diseases
Virology
spatial intratumoral heterogeneity
next generation sequencing
inherent sampling bias
early prostate cancer
confined gleason 3
psa &# 8804
na &# 239
mccl &# 8804
visible prostate tumours
concordant mri lesion
based risk stratification
xlink "> reconcile
xlink "> blood
combined &# 916
reconcile study protocol
underlying molecular landscape
reconcile )</ p
radiomic markers associated
interval mr images
likert score 4
radiological progression events
observational cohort study
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molecular markers
radiomic analysis
intermediate risk
care mri
4 tumours
molecular progression
precise score
molfu score
radiological progression
clinical progression
molecular profile
molecular index
molecular change
identify molecular
tumour tissue
targeted histology
statistical power
specified sub
single centre
recently diagnosed
primary outcome
one year
molfu ).
july 2020
exploiting image
ethics approved
donated tissue
biological samples
active surveillance
62 ).
60 treatment
4 cancers
15 ng
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