RECONCILE study inclusion and exclusion criteria.

RECONCILE study inclusion and exclusion criteria.

<div><p>Introduction</p><p>RECONCILE (ClinicalTrials.gov:NCT04340245) will identify molecular and radiomic markers associated with clinical progression and radiological progression events in a cohort of localised, newly diagnosed Gleason 3 + 4 tumours. Molecular markers will...

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Bibliographic Details
Main Author:	Teresa Marsden (12133267) (author)
Other Authors:	Gerhardt Attard (120990) (author), Shonit Punwani (3547364) (author), Francesco Giganti (727736) (author), Alex Freeman (127608) (author), Aiman Haider (12114733) (author), Anna Wingate (12906113) (author), Norman Williams (5101406) (author), Tom Syer (12133273) (author), Nora Pashayan (64158) (author), Caroline M. Moore (7169102) (author), Mark Emberton (3547379) (author), Clement Orczyk (7311095) (author)
Published:	2024
Subjects:	Medicine Cell Biology Genetics Biotechnology Cancer Infectious Diseases Virology spatial intratumoral heterogeneity next generation sequencing inherent sampling bias early prostate cancer confined gleason 3 psa &# 8804 na &# 239 mccl &# 8804 visible prostate tumours concordant mri lesion based risk stratification xlink "> reconcile xlink "> blood combined &# 916 reconcile study protocol underlying molecular landscape reconcile )</ p radiomic markers associated interval mr images likert score 4 radiological progression events observational cohort study xlink "> &# 916 molecular markers radiomic analysis intermediate risk care mri 4 tumours molecular progression precise score molfu score radiological progression clinical progression molecular profile molecular index molecular change identify molecular tumour tissue targeted histology statistical power specified sub single centre recently diagnosed primary outcome one year molfu ). july 2020 exploiting image ethics approved donated tissue biological samples active surveillance 62 ). 60 treatment 4 cancers 15 ng
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