Image 11_Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization.tif

Image 11_Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization.tif

Introduction<p>There is an urgent need for influenza vaccine strategies that enhance protection against influenza virus drift and across different subtypes. The conserved viral nucleoprotein (NP) is the most abundant viral protein during replication, and a target for broadly protective cellula...

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Autore principale: Ebony N. Gary (2019478) (author)
Altri autori: Abigail R. Trachtman (21841544) (author), Dan Wang (34472) (author), Suman Bharti (9990011) (author), Ying Ye (72583) (author), Nicholas J. Tursi (10166063) (author), Martina Tomirotti (22686932) (author), Jillian Eisenhauer (21841538) (author), Jacqueline D. Chu (21841547) (author), David Custodio Zegarra (22686935) (author), Casey E. Hojecki (22686959) (author), Micki Zheng (22686962) (author), Jayamanna Wickramasinghe (4782693) (author), David B. Weiner (9579320) (author), Ami Patel (139999) (author)
Pubblicazione: 2025
Soggetti:
Genetic Immunology
influenza A virus
nucleoprotein
hemagglutinin
synthetic DNA
multivalent vaccine
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