N-linked glycosylation of rEtpA.

<p>A. Site-specific mass-spectrometry data for rEtpA showing the % occupancy by monohexose, or dihexose, or no glycan (unoccupied) at all 196 asparagine residues analyzed along with the peptide count (right axis and blue line—number of peptides detected in the experiment) and corresponding dom...

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Main Author:	Zachary T. Berndsen (9230176) (author)
Other Authors:	Marjahan Akhtar (10800564) (author), Mahima Thapa (19681706) (author), Tim J. Vickers (7962296) (author), Aaron Schmitz (19681709) (author), Jonathan L. Torres (8551344) (author), Sabyasachi Baboo (574971) (author), Pardeep Kumar (604685) (author), Nazia Khatoon (5561138) (author), Alaullah Sheikh (192291) (author), Melissa Hamrick (19681712) (author), Jolene K. Diedrich (1235706) (author), Salvador Martinez-Bartolome (19681715) (author), Patrick T. Garrett (19681718) (author), John R. Yates III (8072333) (author), Jackson S. Turner (4397776) (author), Renee M. Laird (7817261) (author), Frédéric Poly (427531) (author), Chad K. Porter (9721233) (author), Jeffrey Copps (9230170) (author), Ali H. Ellebedy (8977307) (author), Andrew B. Ward (7832180) (author), James M. Fleckenstein (7901579) (author)
Published:	2024
Subjects:	Biochemistry Microbiology Biotechnology Ecology Immunology Infectious Diseases Virology Biological Sciences not elsewhere classified stimulates adaptive immunity infectious diarrhea annually highly immunogenic resulting div >< p adaptive immunity relevant middle income regions em structures revealed effective bacterial adhesion secreted glycoprotein adhesin mabs directly engage escherichia coli </ promote critical interactions host glycan interactions etpa directs etec coli </ host interaction etec adhesion determined structures decoy regions e </ vaccinated mice toxin delivery terminal domains significantly increased repeat modules mutated etpa monoclonal antibodies intestinal epithelia inhibited etpa general understanding experimental challenge etpa complexes electron microscopy diarrheal severity critical enterotoxigenic cause hundreds blood group
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N-linked glycosylation of rEtpA.

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