Optogenetic stimulation of hippocampal astrocytes has no significant effect on the basal excitatory synaptic transmission.

(A) Experimental timeline of viral injection, surgery, optogenetic stimulation, and electrophysiological experiments. (B) Typical traces of the fEPSPs evoked by various strengths of stimuli in the eYFP and ChR2-eYFP expressing groups (left). The relatio...

Full description

Saved in:

Bibliographic Details
Main Author:	Jae-Hong Kim (124622) (author)
Other Authors:	Nakamura Michiko (19109425) (author), In-Sun Choi (19109428) (author), Yujung Kim (94261) (author), Ji-Young Jeong (9673830) (author), Maan-Gee Lee (1754947) (author), Il-Sung Jang (1754944) (author), Kyoungho Suk (1754950) (author)
Published:	2024
Subjects:	Biochemistry Cell Biology Molecular Biology Neuroscience Physiology Immunology Mental Health Biological Sciences not elsewhere classified neuronal nmda receptors sustained chemogenetic stimulation repeated optogenetic stimulation induced cognitive impairment hippocampal astrocyte activation decreased synaptic long lcn2 ), derived induce cognitive decline hippocampal ca1 astrocytes mice </ p cognitive decline used optogenetic synaptic modulation lcn2 release cognitive disturbances chemogenetic tools aberrant activation underlying mechanisms term potentiation results showed reactive astrocytes metabolic inhibitor ltp ), inflammatory astrocytes high level findings suggest diverse neuropathologies crucial roles
Tags:	Add Tag No Tags, Be the first to tag this record!

Optogenetic stimulation of hippocampal astrocytes has no significant effect on the basal excitatory synaptic transmission.

Similar Items