CUMS increased the concentration of pro-apoptosis factor, while the combination of CUMS and smoke exacerbated these changes by increasing inflammation and dysfunction of BDNF system in the hippocampus.

<p>The concentrations of apoptosis-related factors, neuroinflammatory factors, BDNF, TrkB and P75 by ELISA kits in the hippocampus of the mice. (A, B and C) The concentrations of Bax and Bcl-2, and Bax/Bcl-2 ratio. (D, E and F) The concentrations of BDNF, TrkB and P75. (G, H and I) The concent...

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Main Author:	Bai-Ping Liu (14164799) (author)
Other Authors:	Cai Zhang (163340) (author), Yong-Ping Zhang (11659796) (author), Kang-Wei Li (14164802) (author), Cai Song (4372426) (author)
Published:	2022
Subjects:	Medicine Cell Biology Molecular Biology Biotechnology Developmental Biology Cancer Mental Health Infectious Diseases Chemical Sciences not elsewhere classified tnf -&# 945 possible underline mechanisms p38 &# 945 low survival rate forced swimming behaviors derived neurotrophic factor 90 &# 945 1 &# 946 increased immobility time xlink "> compared related factors cdk1 il )- 1 increased serum corticosterone xlink "> depression blood corticosterone concentration smoke increased trkb induce lung cancer smoke exacerbated depression cums decreased bdnf xlink "> related factors induce depression significantly increased increased p75 cums increased decreased trkb decreased bdnf smoke group smoke caused sucrose preference results suggest positively correlated lung interleukin lung cancer j mice involve inflammation high incidence control group cancer occurrence
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CUMS increased the concentration of pro-apoptosis factor, while the combination of CUMS and smoke exacerbated these changes by increasing inflammation and dysfunction of BDNF system in the hippocampus.

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