Active caspase-3 is increased while p-MLKL is reduced in NRG1 treated SeV infected mouse lungs.

<p><b>(A)</b> Representative images (at 20x magnification) of lung immunohistochemistry showing active caspase-3 stained epithelial cells (arrow heads) in PBS (top panel) and NRG1 treated (bottom panel) (500 ng, daily day-4 to day 0) at day 5 post inoculation SeV. <b>(B)</...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Syed-Rehan A. Hussain (5494103) (author)
مؤلفون آخرون:	Michelle Rohlfing (5494091) (author), Jennifer Santoro (19822554) (author), Phylip Chen (7832030) (author), Kaushik Muralidharan (21169232) (author), Matthew S. Bochter (21169235) (author), Mark E. Peeples (7832042) (author), Mitchell H. Grayson (21169238) (author)
منشور في:	2025
الموضوعات:	Medicine Microbiology Cell Biology Immunology Cancer Mental Health Infectious Diseases Virology reducing alveolar leak natural rodent pathogen found markedly elevated bronchoalveolar lavage fluid protein indicating inhibition promoting homeostatic regulation mouse adapted influenza regulating genes associated inhibiting epithelial necroptosis respiratory viral infections nrg1 protected naïve div >< p necroptosis associated genes respiratory syncytial virus markedly reduced mortality mice made atopic 1 prevents death respiratory infections reduced phosphorylation one protein influenza lead homeostatic maintenance vitro </ unique function significant morbidity sendai virus rna viruses ripk3 </ nrg1 ). iav ). data demonstrate atopic mice airway epithelium
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Active caspase-3 is increased while p-MLKL is reduced in NRG1 treated SeV infected mouse lungs.

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