Hierarchical Deep Spectral Clustering results for AC-20-4.

Hierarchical Deep Spectral Clustering results for AC-20-4.

<p>Left to right: average AFM image, LAFM image, VMD surface representation of atomic structure with maximum silhouette score in each cluster, including zoomed views of ROI (green boxes) outlining prominent residues. LAFM accurately tracks the peak position of these residues in clusters A and...

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Bibliographic Details
Main Author: Creighton M. Lisowski (22756444) (author)
Other Authors: Gavin M. King (1316184) (author), Ioan Kosztin (3917603) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Medicine
Biotechnology
Developmental Biology
Infectious Diseases
Computational Biology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Physical Sciences not elsewhere classified
reconstructing peak positions
molecular dynamics simulations
handle biological macromolecules
demonstrate improved resolution
individual protein conformations
general lafm algorithm
afm image stacks
protein conformation
multiple conformations
work represents
step towards
simultaneously registers
secyeg translocon
recording frequency
native conditions
less effective
flexible proteins
create images
clusters images
automated registration
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