SMRT regulates myotube formation in the differentiation process of C2C12 cells.

<p>(A) Both C2C12-WT and C2C12-SKO cells were induced to differentiate in differentiation medium. The expression of myosin heavy chain 4 (MYH4) in both C2C12-WT and C2C12-SKO cells were assessed by IHC. Myotubes were stained by anti-MYH4 antibody (Green). Nuclei were stained by DAPI (Blue). Th...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Hiroaki Shimizu (440570) (author)
مؤلفون آخرون:	Yasuhiro Horibata (625218) (author), Izuki Amano (5213840) (author), Megan J. Ritter (14203815) (author), Mariko Domae (14203818) (author), Hiromi Ando (14203821) (author), Hiroyuki Sugimoto (625219) (author), Ronald N. Cohen (7207826) (author), Anthony N. Hollenberg (3628670) (author)
منشور في:	2022
الموضوعات:	Biochemistry Medicine Cell Biology Genetics Molecular Biology Physiology Evolutionary Biology Developmental Biology Marine Biology Infectious Diseases Virology Computational Biology two cell lines ppar &# 947 fibroblast growth factor also widely expressed 1 &# 945 similar gene profile receptor inhibitor ameliorated pivotal transcriptional mediator mouse connective tissues tissue specific role thyroid hormone receptors 2 ), indicating adult skeletal muscle lack smrt protein sko cells similar thyroid hormone transcriptional corepressor skeletal muscle resulting gene mouse embryo smrt protein protein profiles xlink "> using crispr strong regulator somatic development smrt plays smrt functions sko cells significant role significant loss receptor signaling recently reported peroxisome proliferator muscle wasting important player immature myoblasts higher expression hepatic lipogenesis global deletion example adipocytes clarify role
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SMRT regulates myotube formation in the differentiation process of C2C12 cells.

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