Supplementary file 1_Selective amino acid formulation enhances anion secretion and restores function in cystic fibrosis mutations.docx

Introduction<p>In cystic fibrosis (CF), most CFTR mutations cause partial (Class II) or complete (Class I) loss of function. Modulators (VX) can improve CFTR function in Class II mutations but are ineffective for Class I mutations and may cause side effects, resulting in tolerability issues wi...

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Main Author: Astrid Grosche (19226524) (author)
Other Authors: Anusree Sasidharan (19226521) (author), Matthias Salathe (3520151) (author), Nathalie Baumlin (9656266) (author), Damiano Angoli (19226530) (author), Sreekala Prabhakaran (11882191) (author), Xiaodong Xu (276342) (author), Sadasivan Vidyasagar (302425) (author)
Published: 2025
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