Maternal par2a mutant embryos display impaired egg activation events and cell division defects.

A: Nomarski images of naturally fertilized and unfertilized, activated eggs from WT, mild and severe par2a mutant females. Chorion elevation and blastodisc formation are variably disrupted. B: Changes in the ratio of chorion lift to e...

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Bibliographic Details
Main Author:	Jiajia Ma (525489) (author)
Other Authors:	Tom J. Carney (1710409) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Microbiology Cell Biology Genetics Molecular Biology Pharmacology Developmental Biology Cancer Science Policy Infectious Diseases Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified sup >++</ sup later blastula cytokinesis failed chorion elevation egg immediately prior activated receptor 2a div >< p critical mechanisms exist vertebrate egg activation failed egg activation serine protease activity zebrafish egg activation egg activation serine proteases protease receptor mechanisms employed critical regulator zebrafish protease zebrafish eggs mediated activation transverse across successful initiation strong evidence severe disruption restoring ca ooplasmic segregation mutants progress long implicated gamete pronuclei endoplasmic reticulum direct injection cleavage furrows also results
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Maternal <i>par2a</i> mutant embryos display impaired egg activation events and cell division defects.

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