The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress

The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress

<p>Lung cancer is one of the leading causes of cancer-related deaths worldwide with limited treatment options available. The anti-tumor effects of the TrxR inhibitor Butaselen (BS/BS1801) on lung cancer and its underlying mechanisms remain unknown.</p> <p>This study utilized lung c...

Fuld beskrivelse

Saved in:

Bibliografiske detaljer
Hovedforfatter:	Yifan Chen (446592) (author)
Andre forfattere:	Guangliang Qiang (296666) (author), Liang Jin (316008) (author), Yan Sun (22436) (author), Guozhou Zhang (22688355) (author), Fengling Hu (3595472) (author), Jinhui Feng (269301) (author), Feng Wei (426184) (author), Shengxin Zeng (22688358) (author), Lixiang Xue (23235) (author), Huihui Zeng (6700337) (author), Shaohua Ma (8746758) (author)
Udgivet:	2025
Fag:	Biochemistry Medicine Microbiology Cell Biology Molecular Biology Pharmacology Developmental Biology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified Lung cancer oxidative stress thioredoxin reductase butaselen apoptosis high-mobility group box-containing protein 1 (HBP1) ubiquitination DNA methylation
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Lignende værker

The E3 ligase Tripartite motif 7 drives the progression of non-alcoholic fatty liver disease by targeting DUSP10 degradation
af: Feng-Juan Yan (21454759)
Udgivet: (2025)

Supplementary Figure S1 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
af: Rumani Singh (17141575)
Udgivet: (2025)

Supplementary Figure S2 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
af: Rumani Singh (17141575)
Udgivet: (2025)

Supplementary Figure S3 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
af: Rumani Singh (17141575)
Udgivet: (2025)

Supplementary Figure S4 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
af: Rumani Singh (17141575)
Udgivet: (2025)

Supplementary Figure S5 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
af: Rumani Singh (17141575)
Udgivet: (2025)

Supplementary Figure S6 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
af: Rumani Singh (17141575)
Udgivet: (2025)

Supplementary Tables from Targeting BCL6 in Gastrointestinal Stromal Tumor Promotes p53-Mediated Apoptosis to Enhance the Antitumor Activity of Imatinib
af: Xiangyu Zeng (17314920)
Udgivet: (2025)

Supplementary file 1_An evergrowing sweet cherry for research and breeding.docx
af: Afif Hedhly (3267840)
Udgivet: (2025)

Oxidative stress resistance of the <i>yqhG</i> mutant.
af: Jianhua Liao (1393228)
Udgivet: (2025)

Supplemental figures for "Exercise enhances antioxidant protein levels in oxidative skeletal muscle via IL-1β"
af: Mami Yamada (1271472)
Udgivet: (2025)

Supplementary Table 1 from Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy
af: Naoshad Muhammad (14960127)
Udgivet: (2025)

Supplementary Table 2 from Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy
af: Naoshad Muhammad (14960127)
Udgivet: (2025)

Supplementary file 1_ER stress in D1-MSNs mediates cocaine-induced behavioral plasticity via the ATF4–SPTLC1 axis.docx
af: Yue Zhao (186573)
Udgivet: (2025)

Targeted strategy by curcumin and tideglusib biomimetic nano-systems alleviates oxidative stress and inflammation under ischemic stroke
af: Jiajia Li (184267)
Udgivet: (2025)

Advancing smart disaster response by leveraging social sensing and mobile technology
af: Sulong Zhou (22683009)
Udgivet: (2025)

Data&Codes
af: Anonymous (22685366)
Udgivet: (2025)

Image 1_APOL1 is a novel prognostic biomarker in thyroid cancer and correlates with immune infiltration.jpeg
af: Jianting Man (22678730)
Udgivet: (2025)

Table 3_APOL1 is a novel prognostic biomarker in thyroid cancer and correlates with immune infiltration.docx
af: Jianting Man (22678730)
Udgivet: (2025)

Table 4_APOL1 is a novel prognostic biomarker in thyroid cancer and correlates with immune infiltration.docx
af: Jianting Man (22678730)
Udgivet: (2025)

Table 1_APOL1 is a novel prognostic biomarker in thyroid cancer and correlates with immune infiltration.docx
af: Jianting Man (22678730)
Udgivet: (2025)

Table 2_APOL1 is a novel prognostic biomarker in thyroid cancer and correlates with immune infiltration.docx
af: Jianting Man (22678730)
Udgivet: (2025)

<b>Underlying data for Wagh & Glickman, PNAS 2025</b>
af: Ajay R Wagh (22679472)
Udgivet: (2025)

Supplementary file 1_Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans.pdf
af: Xueqing Chen (499722)
Udgivet: (2025)

Supplementary file 2_Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans.xlsx
af: Xueqing Chen (499722)
Udgivet: (2025)

Discovery and Characterization of Novel BLIMP‑1 Heterobifunctional Ligand-Directed Degraders
af: Bryan J. Simmons (22676881)
Udgivet: (2025)

Supplementary Table S3 from Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation
af: Wei Cui (16721390)
Udgivet: (2025)

Supplementary Table S4 from Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation
af: Wei Cui (16721390)
Udgivet: (2025)

Supplementary Table S5 from Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation
af: Wei Cui (16721390)
Udgivet: (2025)

Supplementary Table S6 from Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation
af: Wei Cui (16721390)
Udgivet: (2025)

Supplementary Table S7 from Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation
af: Wei Cui (16721390)
Udgivet: (2025)

Supplementary Data from DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations
af: John Gallon (15096459)
Udgivet: (2025)

Development of FBXO22 Degraders and the Recruitment Ligand 2‑Pyridinecarboxyaldehyde (2-PCA)
af: Tian Qiu (156003)
Udgivet: (2025)

Development of FBXO22 Degraders and the Recruitment Ligand 2‑Pyridinecarboxyaldehyde (2-PCA)
af: Tian Qiu (156003)
Udgivet: (2025)

Table S1 from Oxidative Phosphorylation Fueled by Fatty Acid Oxidation Sensitizes Leukemic Stem Cells to Cold
af: Emmanuel Griessinger (16721087)
Udgivet: (2025)

Table S2 from Oxidative Phosphorylation Fueled by Fatty Acid Oxidation Sensitizes Leukemic Stem Cells to Cold
af: Emmanuel Griessinger (16721087)
Udgivet: (2025)

Genome-wide methylation changes upon Caco-2 cells exposure to undigested and digested titanium dioxide nanoparticles
af: Célia Ventura (8440917)
Udgivet: (2025)

Supplementary Table S2 from Metabolomic, DNA Methylomic, and Transcriptomic Profiling of Suberoylanilide Hydroxamic Acid Effects on LPS-Exposed Lung Epithelial Cells
af: Pochung Jordan Chou (14851578)
Udgivet: (2025)

Supplementary Table S3 from Metabolomic, DNA Methylomic, and Transcriptomic Profiling of Suberoylanilide Hydroxamic Acid Effects on LPS-Exposed Lung Epithelial Cells
af: Pochung Jordan Chou (14851578)
Udgivet: (2025)

Supplementary Table S4 from Metabolomic, DNA Methylomic, and Transcriptomic Profiling of Suberoylanilide Hydroxamic Acid Effects on LPS-Exposed Lung Epithelial Cells
af: Pochung Jordan Chou (14851578)
Udgivet: (2025)

Cannot write session to /tmp/vufind_sessions/sess_1j6kngb3gqqckcs7u9tj9vjns2