Shows the decrease in clustering of NKG2D upon inhibition by KIR2DL2 in the x-y plane in the simulation box for Model 2.

<p>The parameters for the simulation are set at the best fit value from our PSO. Kinetic rates describing inhibition are provided in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010114#pcbi.1010114.t001" target="_blank">Table 1</a>...

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Bibliographic Details
Main Author:	Rajdeep Kaur Grewal (12563150) (author)
Other Authors:	Jayajit Das (459147) (author)
Published:	2022
Subjects:	Biophysics Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Information Systems not elsewhere classified target host cells cognate ligands presented inhomogeneous spatial patterns affecting downstream signaling dueling signals initiated early nkg2d signaling silico framework marks nkg2d microclusters plays nkg2d spatial clustering nkg2d signaling silico framework nkg2d microclusters spatial movements silico modeling viral infections time course spatially resolved shown micron show co ring ). pvav1 ), parameter estimation often unclear modeling shows mechanistic roles major improvement key role increasing production imaging experiments g ., dominant role diverse set determine mechanisms centripetal movements activating signals
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Shows the decrease in clustering of NKG2D upon inhibition by KIR2DL2 in the x-y plane in the simulation box for Model 2.

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