Image_2_A zebrafish model of Ifih1-driven Aicardi–Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients.jpeg

Image_2_A zebrafish model of Ifih1-driven Aicardi–Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients.jpeg

<p>Type I interferonopathies are a heterogenic group of rare diseases associated with an increase in type I interferon (IFN). The main challenge for the study of Type I interferonopathies is the lack of a well-founded animal model to better characterize the phenotype as well as to perform fast...

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Bibliographic Details
Main Author: Beatriz Bernal-Bermúdez (17446230) (author)
Other Authors: Alicia Martínez-López (210802) (author), Francisco J. Martínez-Morcillo (11663364) (author), Sylwia D. Tyrkalska (14031986) (author), Teresa Martínez-Menchón (11663382) (author), Pablo Mesa-del-Castillo (17446233) (author), María L. Cayuela (11663391) (author), Victoriano Mulero (75704) (author), Diana García-Moreno (560071) (author)
Published: 2025
Subjects:
Immunology
Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)
Autoimmunity
Cellular Immunology
Humoural Immunology and Immunochemistry
Immunogenetics (incl. Genetic Immunology)
Innate Immunity
Transplantation Immunology
Tumour Immunology
Immunology not elsewhere classified
Genetic Immunology
Animal Immunology
Veterinary Immunology
type I IFN
IFIH1
zebrafish avatar
autoimmunity
drug screening
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