Image 1_Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency.tiff

<p>Neutrophilic inflammation and a high level of free α-defensins are main features of chronic airway inflammation in alpha-1 antitrypsin-deficient (AATD) individuals. Despite the antimicrobial activities of α-defensins by direct bacterial killing and by modulation of immune responses, AATD in...

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Main Author: Jungnam Lee (35825) (author)
Other Authors: Naweed Mohammad (17618796) (author), Kyudong Han (35824) (author), Tammy Flagg-Dowie (20710838) (author), Maria Magallon (20710841) (author), Mark L. Brantly (7950518) (author), Karina A. Serban (19704326) (author)
Published: 2025
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