Loss of MAP4K4 expression causes a decrease in the number of neutrophils.

<p>(A) Scheme of all-trans-retinoic acid (ATRA)-induced neutrophil differentiation of the hematopoietic HL-60 cell models (left); flow cytometry analysis of the neutrophil marker CD11b has validated that ATAR can induce differentiation of HL-60 cells into neutrophils. This is demonstrated by h...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Guihua Wang (286390) (author)
مؤلفون آخرون:	Dan Zhang (51283) (author), Zhifeng He (5136524) (author), Bin Mao (2001418) (author), Xiao Hu (233579) (author), Li Chen (5749) (author), Qingxin Yang (5561867) (author), Zhen Zhou (184390) (author), Yating Zhang (218669) (author), Kepan Linghu (20890196) (author), Chao Tang (10925) (author), Zijie Xu (10648835) (author), Defu Liu (1701892) (author), Junwei Song (4060921) (author), Huiying Wang (807020) (author), Yishan Lin (9159326) (author), Ruihan Li (6611660) (author), Jing-Wen Lin (1734628) (author), Lu Chen (75170) (author)
منشور في:	2025
الموضوعات:	Cell Biology Genetics Molecular Biology Physiology Immunology Developmental Biology Hematology Computational Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Information Systems not elsewhere classified novel regulatory mechanism mice induced neutropenia hematopoietic stem cells activated protein kinase robust prediction model molecular regulators involved identify neutrophil regulators identified pipeline leads div >< p proteins involved model training learning pipeline work presents utilized positive silico </ short lifespan random forest physiological characteristics phosphorylation level phosphorylating apoptosis pathological relatedness neutrophil differentiation neural network macrophage progenitor identifying mitogen gmp ), gene knockout gene conservation continuous replenishment cell apoptosis bone marrow 4 (<
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Loss of MAP4K4 expression causes a decrease in the number of neutrophils.

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