Rethinking assumptions of disorder in highly charged regions.

a The same set of predictors that have been associated with disordered regions turn out to also be compatible with a fully structured helical region. b Present leading-edge methods for disorder and structure prediction disagree completely and also fail...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Catherine G. Triandafillou (17174814) (author)
مؤلفون آخرون:	Rosalind Wenshan Pan (17174817) (author), Aaron R. Dinner (115250) (author), D. Allan Drummond (17174820) (author)
منشور في:	2023
الموضوعات:	Biophysics Biochemistry Evolutionary Biology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified xlink "> understanding using recent advances sequences dictate physicochemical often pursued separately highly charged regions features often used charged residues ), structure far better conserved secondary structure regions form well high charge density established heuristics based low sequence complexity low hydrophobicity structure prediction stable structure helical structure two approaches structured helices routinely presumed results underscore previously appreciated molecular biology length helices experimental structures dynamical properties diverse proteomes determine function defining challenge also compatible
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Rethinking assumptions of disorder in highly charged regions.

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