Figure 1 from Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma

Schema for AI-based identification of a repurposed drug combination strategy for ACVR1-mutant DIPG. The BenevolentAI knowledge graph was employed to identify approved drugs with potential potency against ACVR1 and sufficient CNS penetration to be a rational therapy for ch...

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Detalles Bibliográficos
Autor principal:	Diana M. Carvalho (5608127) (author)
Otros Autores:	Peter J. Richardson (15118576) (author), Nagore Olaciregui (15118579) (author), Reda Stankunaite (15118582) (author), Cinzia Lavarino (15107701) (author), Valeria Molinari (15110798) (author), Elizabeth A. Corley (15118585) (author), Daniel P. Smith (11197155) (author), Ruth Ruddle (15022002) (author), Adam Donovan (1385493) (author), Akos Pal (1385445) (author), Florence I. Raynaud (1269372) (author), Sara Temelso (15118588) (author), Alan Mackay (20972) (author), John P. Overington (15118591) (author), Anne Phelan (76952) (author), David Sheppard (1893940) (author), Andrew Mackinnon (194271) (author), Bassel Zebian (5986940) (author), Safa Al-Sarraj (219896) (author), Ashirwad Merve (15118594) (author), Jeremy Pryce (15118597) (author), Jacques Grill (15015216) (author), Michael Hubank (15104113) (author), Ofelia Cruz (9950930) (author), Andres Morales La Madrid (343870) (author), Sabine Mueller (5350358) (author), Angel M. Carcaboso (15053699) (author), Fernando Carceller (14945229) (author), Chris Jones (25458) (author)
Publicado:	2025
Materias:	Cancer Therapeutic Research and Development Clinical Research and Trials Methods and Technology Clinical-Stage Research CNS Cancers Gliomas, Glioblastomas Computational Methods Algorithms Drug Discovery Technologies Drug Targets Pediatric Cancers Pharmacology Pharmacokinetics and pharmacodynamics
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Figure 1 from Repurposing Vandetanib plus Everolimus for the Treatment of <i>ACVR1</i>-Mutant Diffuse Intrinsic Pontine Glioma

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